CNS Despair Promethazine HCl Oral Resolution may possibly impair the psychological and/or Actual physical talents essential for that general performance of probably harmful tasks, like driving a car or truck or working equipment. The impairment could be amplified by concomitant usage of other central-nervous-system depressants including Liquor, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, typical anesthetics, tricyclic antidepressants, and tranquilizers; for that reason, this kind of brokers should really both be eradicated or given in diminished dosage in the presence of promethazine HCl (see Safeguards – Information and facts for Individuals and Drug Interactions).

Sedating medicine could induce confusion and in excess of-sedation while in the elderly; elderly patients frequently really should be began on reduced doses of Promethazine HCl Oral Solution and noticed carefully.

Promethazine HCl might be applied by itself or being an adjunct to narcotic analgesics throughout labor (see DOSAGE AND ADMINISTRATION). Minimal information advise that use of Promethazine in the course of labor and supply doesn't have an appreciable effect on the period of labor or supply and won't improve the chance of need for intervention in the newborn.

Uncontrolled spasms of your deal with and neck muscles, or muscles of Your whole body, arms, and legs (dystonia). These muscle mass spasms might cause irregular actions and system positions, and speech challenges. These spasms might transpire just after one particular dose of PROMETHAZINE WITH CODEINE ORAL SOLUTION. Convey to your healthcare company In case you have any of such indicators. Elevated hazard of seizures in people with seizure Conditions. For those who have a seizure disorder, PROMETHAZINE WITH CODEINE ORAL Answer may perhaps boost how often you've got seizures. Very low blood pressure level. A sudden drop in blood pressure level can come about in many people during remedy with PROMETHAZINE WITH CODEINE ORAL SOLUTION and this may perhaps result in you to sense dizzy, faint, lightheaded, or weak, specially when you stand up (orthostatic hypotension).

Stimulation could be apparent, especially in kids and geriatric patients. Convulsions might almost never arise. A paradoxical-kind reaction is described in kids getting single doses of seventy five mg to one hundred twenty five mg orally, characterized by hyperexcitability read more and nightmares.

The concomitant usage of anticholinergic medications with Promethazine with Codeine Oral Answer may possibly maximize threat of urinary retention and/or intense constipation, which can lead to paralytic ileus [see Warnings and Safeguards ( five.eleven) ]. Check clients for indications of urinary retention or reduced gastric motility when Promethazine with Codeine Oral Answer is utilized concomitantly with anticholinergic medicines.

Check with your healthcare company When you have any questions on this info. Prior to deciding to get PROMETHAZINE WITH CODEINE ORAL Option, tell your healthcare more info company about your entire medical ailments, such as for those who: Possess a drug dependancy

Absorption Codeine is absorbed from the gastrointestinal tract with utmost plasma concentration occurring sixty minutes post administration. The existence of a substantial-Excess fat, substantial-calorie food did not noticeably influence the PK of codeine.

Stimulation may very well be evident, specifically in young children more info and geriatric people. Convulsions might not often come about. A paradoxical-type reaction more info has become claimed in little ones acquiring single doses of 75 mg to one hundred twenty five mg orally, characterized by hyperexcitability and nightmares.

Don't flush down a bathroom or pour down a drain Except you might be instructed to take action. Check using your website pharmacist When you have questions about the best way to throw out medications. There may be drug just take-back again plans close to you. Purchaser Info Use and Disclaimer

Speak with the health care provider. Prior to your child requires promethazine syrup, inform the health care provider if your son or daughter is using any medication that can cause respiration difficulties. There are plenty of prescription drugs that could do this. Talk to the medical professional or pharmacist if You're not confident. Utilizes of Promethazine Syrup:

Results to the Cardiovascular Procedure Codeine produces peripheral vasodilation which may result in orthostatic hypotension or syncope. Manifestations of histamine release and/or peripheral vasodilation may consist of pruritus, flushing, crimson eyes and sweating and/or orthostatic hypotension.

Sedation in the two small children and adults, and also aid of apprehension and creation of light rest from which the client may be very easily aroused.

These indicators contain sluggish or shallow respiration, issues or noisy respiration, confusion, a lot more than regular sleepiness, issues breastfeeding, or limpness. For those who notice any of such signals, prevent offering the medication and seek out health-related focus right away by intending to an crisis home or calling 911.